GCG and type 2 diabetes mellitus: Ile-Pro, Met-Pro, Val-Pro, and Leu-Pro are dipeptides with direct inhibitory activity against dipeptidylpeptidase-IV, which metabolizes the insulin-tropic hormone glucagon-like peptide-1, used to control postprandial hyperglycemia in type 2 diabetes, and to prevent and treat type 2 diabetes [43].