Reduced anxiety-like behaviors Decreased neuroinflammatory responses Inhibition of TLR-4/NF-κB pathwayStimulated Nrf2 signaling pathwayIncreased BDNF, NE, 5-HTRepaired synaptic impairmentsRegulated BDNF/TrkB/CREB signaling pathway;. This evidence concerns the gene TLR4 and Anxiety.