ESPL1 and migraine disorder: Through exome sequencing, we identified an entire list of migraine-associated (p-value < 0.00001) variants and prioritised 17 as the most significant (9.091 × 10−05) functional variants distributed among 12 genes (RETNLB, SCAI, ADH4, ESPL1, CPT2, FLG, PPP4R1, SERPINB5, ZNF66, ETAA1, EXO1 and CPA6) in the Saudi females suffering from migraine.