Interestingly, the expression status of RNIP3, CASP8, DDX58, FLT3, HDAC9, ID1, LEF1, RIPK3, TLR3, and TNFSF10 (high or low expression) was heterogeneous among the four tumors, indicating the dual role of NRGs in gynecological tumors to a certain extent. Here, RIGI is linked to female reproductive system neoplasm.