The proportion of MAPK8IP2 genetic alteration in PCa was 2.6% (Fig. 3A), which consisted of missense mutation (Fig. 3B), amplification, and deep deletion were 0.2% (2/999), 0.8% (8/999), and 1.6% (16/999), respectively. The gene discussed is MAPK8IP2; the disease is posterior cortical atrophy.