The odds of showing a carotid plaque were 4.29 times higher (95% CI 1.16, 15.91, p < 0.05) among those participants genotyped as APOE e4e4 than those genotyped as APOE e3e3 after adjusting for BMI, hypertension, dyslipidemia, diabetes, MVPA, VO2max, and aMED score (Table 2). This evidence concerns the gene APOE and hypertensive disorder.