In agreement with the present study, many reports worldwide disclosed this association between ACE I/D polymorphism and HTN, i.e., in Nigerian [20], Burkina Faso [35], Chinese [12, 13], Brazil [18], South Indian [15], Chile [37], Arabian [21], and Bangladeshi [22] populations have suggested an association between ACE- DD polymorphism with a higher incidence of hypertension. Here, ACE is linked to hypertensive disorder.