Solid Tumors: Using the cervical HeLa cancer cell line, cranberry proanthocyanidin extract (CPAC, from Vaccinium macrocarpon, up to 100 μg/mL, 4 h) disrupted actin polymerization along with delocalization of VASP to focal adhesions and α-actinin/paxillin [39]. The gene discussed is VASP; the disease is cancer.