Solid Tumors: In a dimethylbenzanthracene (DMBA)-induced hamster model of oral cancer, blueberry supplementation (200 mg/kg) reduced tumor burden; this outcome was associated with reduced JAK2 and STAT3 RNA expression and reduced p-JAK2 and p-STAT3 protein (along with reducing its nuclear translocation) [139]. The gene discussed is JAK2; the disease is neoplasm.