After establishing a CD4+ T cell recruitment deficit as the primary reason for the reduced T cell infiltrate in kidneys of steroid-treated animals, we assessed the chemokine receptor expression profile of renal CD4+ T cells in cGN because the chemokine/chemokine receptor system is the key regulator of directional T cell trafficking under inflammatory conditions (15, 18, 19). This evidence concerns the gene CD4 and childhood gender nonconformity.