ASCi.v tumors were highly aggressive, with host mice requiring sacrifice at a median of 40.4 (nude, n=7) and 25 (C57BL/6, n=15) days post-injection, in comparison to the median latency of KL;ASC GEMMs of 79 days post-tumor initiation (Nagaraj et al., 2017). This evidence concerns the gene KL and neoplasm.