EGFR and neoplasm: To further explore both the therapeutic response of transplanted tumor cells following lung colonization and the corresponding impact on host survival, ASCi.v./C57BL/6, mice were treated with vehicle, AF or the EGFR inhibitor erlotinib (ER) from 10 days post transplantation and sacrificed when they presented with physical signs of disease burden or exhibited 20% body weight loss.