STK11 and neoplasm: Our previous studies in mice have revealed that selective expression of the oncogenic KrasG12D allele in combination with Lkb1 deletion (KL) in lung CC10 cells leads to formation of aggressive ASC lesions, in addition to other tumor histotypes, while ASC histopathology was not observed in tumors arising from SPC cells harboring the same genetic mutations (Nagaraj et al., 2017).