Moreover, in Swedish subjects naive for diabetes treatment and grouped by glycemic status, Intestinimonas was found to be depleted in the group with impaired fasting glucose (IFG) [173], while an increased abundance of Intestinimonas butyriciproducens and Akkermansia muciniphila has been reported, together with improvements in glucose and insulin sensitivity, in high cardiometabolic risk subjects following an MD [174,175]. The gene discussed is INS; the disease is diabetes mellitus.