In the present experiment, hepatic glucose uptake key proteins (GLUT1, GLUT2) were upregulated in NCUG compared to Normal, and relatively, hepatic glucose transport proteins (GLUT1, GLUT2, GLUT4) expression was downregulated in CUG compared to NCUG, which may be one of the reasons for the reduced glucose tolerance in CUG-IUGR offspring. The gene discussed is SLC2A4; the disease is fetal growth restriction.