The miR-126 has been consistently associated with T2D in the literature [59] and has been shown to regulate vascular integrity and angiogenesis [59] through Notch1 inhibitor delta-like 1 homolog (Dlk1) [60] and the argonaute-2 (Ago2)/Mex3a complex [61]. The gene discussed is AGO2; the disease is type 2 diabetes mellitus.