Immunosuppressed mice were treated with a placebo, ibrexafungerp (30 mg/kg, po, BID), liposomal amphotericin B (LAMB, 10 mg/kg, IV, QD), posaconazole (POSA, 30 mg/kg, po, QD), a combination of ibrexafungerp + LAMB, or a combination of ibrexafungerp + POSA 24 h post-infection, and continued for 7 days for ibrexafungerp and POSA and 4 days for LAMB. This evidence concerns the gene GRAMD1B and infection.