It is well known that males [23,24], a spontaneous type 1 BrS ECG [25], the presence of symptoms (such as arrhythmic syncope and documented VT/VF) [26], SCN5A mutations [27], and various electrocardiographic markers [28] are shown to be significant predictors of an SCD. This evidence concerns the gene SCN5A and Schnyder corneal dystrophy.