ESR1 and breast cancer: By analyzing the tissues of 46 patients affected by different histological types of breast cancer (i.e., infiltrating ductal not otherwise specified, infiltrating ductal comedo, lobular invasive, mucinous, medullary), the expression of NGFR/p75NTR was associated with a longer disease-free survival, in addition to ER positivity, small tumor dimension, low histologic grade (G1–G2), old age and menopause [83].