NGF and cancer: In 2008, Adriaenssens et al. [82] confirmed the high expression of NGF, particularly concentered in the epithelial cancer cells, in several histological types of breast cancer (i.e., invasive ductal, invasive lobular, colloid, apocrine, epidermoid metaplastic, tubular and intracanal carcinomas), through the immunostaining with anti-NGF of human breast cancer tissue sections obtained from a series of biopsies.