MAP2K7 and neoplasm: In addition, a recent study in a population of TNBC cells reported an overexpression of NGFR/p75NTR and an interaction between NGFR/p75NTR and TrkC receptors which affects tumor growth and metastasis through the Trk MEK-ERK1-ZEB1 and PI3K-AKT signaling pathways [15].