NGF and breast carcinoma: Chakravarthy et al. [17] demonstrated that the knock-down of NGFR/p75NTR using short hairpin RNA (shRNA) or small molecule inhibition of NGF-NGFR/p75NTR interaction (i.e., Ro 08-2750) sensitized TNBC cells to the apoptosis induced by the cytotoxic/genotoxic drugs used as adjuvant therapies in breast cancer treatment.