NFE2L2 and viral infectious disease: Viral infections can induce the secretion of pro-inflammatory cytokines, the activation of innate immunity, enhanced lipid peroxidation, the production of free radicals and the concomitant depletion of glutathione (GSH) and inhibiting nuclear factor (erythroid-derived 2)-like 2 (NRF2) in epithelial cells of the respiratory tract [77].