High concentrations of the inflammatory chemokines in the triple co-culture (I-TAC/CXCL11, IP-10/CXCL10, MCP-1/CCL2, MCP-2/CCL8, MDC/CCL22, MIG/CXCL9, MIP-1α/CCL3, IL1β, ENA-78/CXCL5, Gro-α/CXCL3, IL6, and IL8/CXCL8), predominantly secreted by PBMCs, may indicate the involvement of various cell populations in the formation of chronic inflammation typical of a natural tumor and the antitumor effects of some populations of immune cells from PBMC fractions. This evidence concerns the gene CCL22 and neoplasm.