The co‐expression and localization levels of MCT4, GLUT1, IL‐1β, NLRP3, MMP3, and p‐NF‐κB increased by the 14‐day timepoint in chondrocytes and immune cells in our in vivo model of septic arthritis (Fig 1L; Appendix Fig S2C). Here, NLRP3 is linked to bacterial arthritis.