LRG1 and posterior cortical atrophy: As in the Martini cohort, the time to BF in the CuPCa cohort, which overall represented a more aggressive PCa population (Table 1), was shorter for the LRG1-low group than for the LRG1-high group (Fig. 2B), which was corroborated by an association with higher EAU risk group (Supplementary Table 2).