In colorectal cancer Lewis glycans on CEA drove impairment of monocyte-derived (mo) DCs’ function upon binding of DC-SIGN and subsequent Th2/Treg responses (54), whereas in ovarian adenocarcinoma sialic acids on MUC1 triggered antitumor activities of macrophages through Dectin-1 and CD206 (75). Here, MRC1 is linked to colorectal cancer.