Though the exact relationship between radiation injury and NLRP3 inflammasome has not yet been illustrated, fecal microbiota transplantation was found to inhibit the expression of inflammasomes components (NLRP3, ASC, caspase-1, and IL-1β) in rat brain, thus ameliorating stress-induced depression-like behaviors (119, 120). This evidence concerns the gene NLRP3 and depressive disorder.