The ICAM1 expression was negatively correlated with tumor purity in KIRC and positively correlated with the infiltration levels of B cells (r=0.339, P=8.28e-14), CD8+ T cells (r=0.174, P=2.57e-04), CD4+ T cells (r=0.182, P=8.56e-05), macrophages (r=0.201, P=1.76e-05), neutrophils (r=0.444, P=1.67e-23), and DCs (r=0.385, P=1.59e-17) in KIRC tissues (Figure 5B). The gene discussed is CD4; the disease is neoplasm.