Hence, we also attempted to probe the functions and mechanisms of GCLM in BCa, we demonstrated that GCLM is overexpressed in BCa and its overexpression indicates dismal prognosis, knockdown of GCLM can significantly suppress the colony formation ability and migration ability of BCa cells, we also found that GCLM might be correlated with immune infiltration in BCa, and can serve as a tumor promotor and immunological biomarker in BCa. This evidence concerns the gene GCLM and neoplasm.