For ovarian cancer risks, guidelines from the National Comprehensive Cancer Network (NCCN) suggest that transvaginal ultrasound and CA-125 may be offered at the clinician’s discretion to BRCA1/2 carriers who have not elected for risk-reducing salpingo-oophorectomy (National Comprehensive Cancer Network (NCCN), 2021a). Here, BRCA1 is linked to ovarian carcinoma.