When considering the two GWASs individually, only one independent genome-wide significant SNP, rs13071258, mapped to the gene cluster of SLC6A20, LZTFL1, CCR9, FYCO1, CXCR6, and XCR1, with p = 9.97 × 10−10 and beta = 0.43, emerged from the male GWAS, while in the corresponding female GWAS, the SNP displayed moderate association signal with COVID-19 hospitalization (p = 4.12 × 10−5; beta = 0.34). This evidence concerns the gene XCR1 and COVID-19.