TRIM21 and COVID-19: Surprisingly, when comparing the expression of these genes in blood samples from COVID-19 patients with healthy controls in the COVID-19 expression database COVID19 db (Thair et al., 2021; Zhang et al., 2022), we found eight genes adjacent to five SNPs, including rs1134004 (GADD45G), rs140657166 (TRIM29 and PVRL1), rs148143613 (KNDC1 and STK32C), rs2443615 (PGAP2 and TRIM21), and rs2924725 (CSMD1), are DEGs between blood of COVID-19 patients and healthy controls (multiple adjusted significance p < 0.015; one-way ANOVA test; Figure 2C).