Consistent with the results mentioned above, the levels of IKZF1 and IKZF3 were highest in immunocytes and lowest in SKCM cells, which further indicates the function of IKZF1 and IKZF3 in the immune response to tumor cells and indicates the status of immunocyte infiltration in the TME (Figures 7B,D). Here, IKZF3 is linked to neoplasm.