Moreover, in addition to indicators that evaluate the disease progression of cancer (pathological TNM, depth of invasion, lymph node metastasis, poor differentiation), preoperative sarcopenia (for men), decreased SMA (for men), SFA, SFI, SV (for women), and SM-RA (especially for men) were also significantly associated with lower 5-year OS in GC patients. Here, SMN1 is linked to metastatic malignant neoplasm in the lymph nodes.