Interestingly, of these 35 positive patients, 51.4% (18/35) still had seropositive MOG-IgG and 94.3% (33/35) were identified as true ADEM patients, while the other two were diagnosed as NMOSD or ADEM-ON patients during the follow-up period. The gene discussed is MOG; the disease is acute disseminated encephalomyelitis.