In the current study, it was decided to investigate the effect of endometritis in gilts on (1) the density and distribution of nerve fibers stained for the pan-neuronal marker protein gene product (PGP)9.5 and CGRP in the myometrium, (2) the expression levels of CRL mRNA and protein in the myometrium, and (3) the participation of CGRPR in CGRP-elicited uterine amplitude and frequency of contractions. Here, CALCA is linked to endometritis.