AIF1 and Alzheimer disease: We performed immunohistochemical staining for Iba1 and the analysis showed microgliosis across CA1, CA3, DG and SB in WT and Tg-AD male and female rats (Fig. 3A,B, whole hippocampus, C and D respective high magnification panels, shown for Tg-AD rats; amyloid plaques, red; microglia, green; amyloid plaques/microglia co-localization, yellow, indicated by white arrow heads).