MRC1 and carcinoma: Among traditional prognostic variables studied in the 5-year survival analysis, OS was significantly shorter in case of advanced UICC stage (p < 0.0001, Fig. 2e), grade 3 (p = 0.0031, Fig. 2g), right-sided tumors (p = 0.012, Fig. 2h), and carcinomas with mucinous or signet ring cell morphology (p = 0.046, Fig. 2f), whereas CSS was worse in tumors with advanced UICC stages (p < 0.0001, Fig. 3e), grade 3 (p = 0.012, Fig. 3g), right-sided tumors (p = 0.012, Fig. 3h), and MMR-proficient CRCs (p = 0.028, Fig. 3d)—see Supplementary Table 2.