After infection of U87 and LN229 cells with Lv-HOXA11-AS alone and together with c-Jun siRNA, RT-qPCR and western blotting analyses showed that HOXA11-AS-induced Tpl2 mRNA and protein expression was significantly reduced by c-Jun depletion (Figs. 5I–J and S17D). This evidence concerns the gene JUN and infection.