In comparison with our mRNA sequence results, which showed 404 upregulated mRNAs in Lv-HOXA11-AS-infected U87 cells, we found that only CTHRC1, a critical gene promoting tumor progression and metastasis including glioma, overlapped with the let-7b-5p target set (Fig. 3A, right). Here, CTHRC1 is linked to glioma.