PRMT3 and glioblastoma: Western blotting further indicated that the expression of PRMT3 in multiple GBM cell lines and patient-derived GBM stem cell lines (GSCs) was higher than that in normal human astrocytes as well as in a normal brain glial cell line (HEB) [29] and a microglia cell line (HMO6) [30] (Fig. 1F and Supplementary Fig. 1).