To further assess the function of PRMT3 in the regulation of metabolic programs in GBM cells, we performed metabolomics analyses by ultra-high pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) [37] using GSC20 cells treated with control shRNA- or shPRMT3 (Supplementary Table 1). Here, PRMT3 is linked to glioblastoma.