Deletion of IL‐6 from cancer cells also reduced Il‐6 mRNA expression in m.qu., iWAT, and gWAT of CHXIL6KO mice (Figure S6D) and resulted in a drastic reduction of plasma IL‐6 concentrations (−94%) as well as p‐STAT3 (Tyr705) levels in iWAT (−60%) and m.qu. The gene discussed is STAT3; the disease is cancer.