We saw a significant reduction in total immune cells (CD45+) in Tlr2−/− tumor-bearing lungs (Figure 3C), and this was primarily driven by a reduction in alveolar macrophages (SiglecF+CD11c+) and monocytes (SiglecF−CD11b+Ly6C+), but the reduction in monocytes did not reach statistical significance (Figures 3B and 3C). This evidence concerns the gene ITGAX and neoplasm.