CALCA and Sepsis: Additionally, as demonstrated in figure 3, this study found no significantcorrelation between the peripheral ischemic microvascular reserve (∆ PPI peak, %)and variation in the neuropeptide CGRP (p = 0.41) and SP (p = 0.26) levels (∆neuropeptide levels, %) within the first 24 hours of sepsis diagnosis afterappropriate hemodynamic resuscitation.