After literature and database searches (e.g., DDG2P, SFARI Gene, OMIM, PubMed), filtering for GTEx brain tissue expression, and pLI intolerance as mentioned above, we highlight five genes (PABPC1, MARK2, SF3B2, CDKN2AIP, and RTF1) as compelling candidates with a potential association with NDDs and are replicated by a case-control design with autism probands. This evidence concerns the gene PABPC1 and autism.