SPT is essential for the viability of all eukaryotic cells, and mutations of SPT are linked to hereditary sensory neuropathy type 1 (HSAN1) and early‐onset amyotrophic lateral sclerosis (ALS; Bode et al, 2015; Mohassel et al, 2021). The gene discussed is SPTLC1; the disease is amyotrophic lateral sclerosis.