Although in our study the amount of AMH was not meaningfully different between thegroups, the higher levels of FSH in some patients and a diminished number of totaland mature oocytes in advanced endometriosis compared with less severe endometriosisenables us to speculate that progression of disease per se is associated withreduced ovarian reserve, but this does not translate into better fertilizationrates, which were the same as in women with the most severe forms of diseasecompared to women with milder forms of endometriosis or other causes ofinfertility. The gene discussed is BRD2; the disease is endometriosis.