For GBM, a total of 7 SNPs have been reported to be associated with the risk of GBM (effect sizes ranging from 1.15 to 1.3) in White populations, including rs12752552 (1p31.3; RAVER2), rs1920116 (3q26.2; LRRC31), rs11233250 (11q14.1; FAM181B), rs3851634 (12q23.3; POLR3B), rs2562152 (16p13.3; RHBDF1), rs10852606 (16q12.1; HEATR3), and rs2235573 (22q13.1; SLC16A8). The gene discussed is SLC16A8; the disease is glioblastoma.