In a recent study, Li and colleagues have performed a Chinese GWAS for glioma with 485 cases and 485 healthy controls and found a significant East Asian specific low-frequency variant (EAFEast Asian = 0.01; EAFWhite = 0.28) with a large effect on 19p13.12 (rs688755; OR = 3.55; CYP4F12)63. The gene discussed is CYP4F12; the disease is glioma.