BRCA1 and ductal breast carcinoma in situ: Similarly, the study by Liu and co-workers [21] reported that among women diagnosed with DCIS and genotyped for BRCA PSVs, the incidence of DCIS in BRCA2 PSVs was higher than that of BRCA1 PSV mutation (27.5%—8/29 versus 3%—1/33) (p = 0.009) [21].