We previously reported that SWDs (Fig. 4A), the electrophysiological correlate of absence seizures, are significantly more prevalent in Syngap+/Δ−GAP rats than in littermate controls.17 We hypothesized that SWDs may correlate with time spent in specific brain states as well as cortical connectivity. This evidence concerns the gene SYNGAP1 and Generalized non-motor (absence) seizure.