Figure 1 demonstrates that the levels of IFN-γ (p <0.0001) IL-6 (p< 0.001), IL-10 (p < 0.001), IL-12 (p < 0.0001), IL-17 (p < 0.0001), and IL-23(p < 0.0001) were all significantly greater in PV patients than in controls, although the levels of IL-4 were comparable in both groups. Here, IL4 is linked to acquired polycythemia vera.