TNF and obesity due to melanocortin 4 receptor deficiency: By the correlation analysis, we identified 35 key genera, which were significantly correlated with features of obesity (body weight gain), dyslipidemia (TC, TG, HDL‐C, and LDL‐C), proinflammatory cytokines (serum IL‐6, IL‐1β, and TNF‐α), and LPS (Figure 6c).