Three of the top 5 trans interacted RNAs from pseudogenes (connectivity > 90) were dynamic, including AC004980.7, SUZ12P, and GUSBP1. GUSBP1 had large structural variation in HepG2, and its copy number variation was observed in 14% of colorectal cancer patient cohort [54, 55]. The gene discussed is GUSBP1; the disease is colorectal cancer.