Quantitative real-time PCR analysis of 30 HCC tissues showed that the circRanGAP1high group’s NRAS levels were more than that of the circRanGAP1low group (Fig. 6C), and NRAS levels in the miR-27b-3phigh group were decreased as compared with a miR-27b-3plow group (Fig. 6D). This evidence concerns the gene NRAS and hepatocellular carcinoma.