AGO2 and hepatocellular carcinoma: Firstly, an online database: circRNA Interactome (https://circinteractome.nia.nih.gov/index.html) suggests enhanced Ago2, circRanGAP1 region occupancy in the (Additional file 1: Fig S2A), secondly, we demonstrated that circRanGAP1was predominantly located in the HCC cells cytoplasm through nuclear/cytosol fractionation and fluorescence in situ hybridization (FISH) assays.