CD274 and hepatocellular carcinoma: Given that the molecular weight of PD-L1 in the present study was around 45 kDa, a molecular weight was closed to that of N-glycosylated PD-L1, we asked whether spermine-induced nuclear localization of β-catenin transcriptionally upregulates STT3 isoforms, leading to PD-L1 glycosylation and stabilization in HCC.