Peifer [16] sequenced the whole exon of 69 BPCs samples and found that chromatin remodeling gene mutations were often occurred in BPCs, such as MEN1, PSIP1 and ARID1A, but gene mutations like RB1 and TP53, which are usually found in lung cancers, were not common in BPCs. Here, TP53 is linked to lung carcinoma.