(2) We also did not detect a high expression of Etv2 (embryonic EC) [60–62], Dll4 and Vegfr2 (tip cells) [63, 64] , or Bst1 (self-renewal EC) [65] in healing ECs, indicating its unique role during brain ischemia (Additional file 2: Table S2). Here, ETV2 is linked to brain ischemia.